Published in Scientific Bulletin. Series F. Biotechnologies, Vol. XXIV
Written by Getuța DOPCEA, Alina Elena NANU, Ioan DOPCEA, Călina Petruţa CORNEA, Camelia Filofteia DIGUȚĂ, Florentina MATEI
Povidone iodine (PVP-I) is a valuable, widespread antiseptic that could trigger bacterial cross-resistance to antibiotics when used at sub-lethal concentrations, although no acquired bacterial cross-resistance has been reported for PVP-I. In this study are assessed the changes in the antimicrobial susceptibility profile of Staphylococcus aureus and Staphylococcus epidermidis strains after five exposures to 0.3125 % PVP-I. For all Staphylococcus epidermidis tested strains the mean of the minimum inhibitory concentrations (MICs) and of the minimum bactericidal concentrations (MBCs) significantly decreased after repeated exposures to sub-lethal concentrations of PVP-I compared to the initial values. There was no significant change from baseline in mean results of the disk diffusion test of any antibiotic for the tests performed on the analysed strain.
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